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Sleep Is the Last Unprotected Hour

Why 80% of insulin automation's benefit happens at night - and why most people with diabetes still face it alone.

Neal sits down with co-founders John Sjolund (CEO) and Jon Brilliant(CFO) of Luna Diabetes, two serial diabetes tech founders building what they call “sleep only automation” - the world’s smallest patch pump designed to automate insulin delivery while you sleep. With over 1700 nights of real-world wear and a pivotal study on the horizon, Jon and John make the case that nighttime is where the biggest gains in diabetes management are hiding - and almost no one is solving for it. Neal shares a personal connection through his father’s decades-long journey with Type 1, and the conversation closes with taco picks spanning a hidden Sorrento Valley gem and an upscale Palo Alto staple.

Key Topics

  • Why 80%+ of glucose-lowering automation benefit happens at night

  • The founding story: from a Hannah Montana watch to the world’s smallest patch pump

  • Sleep disruption as the #1 reported issue among people with diabetes

  • Building trust through consistency in an intimate use case

  • Capital efficiency in medtech: $40M to market vs. the $200M industry average

  • The disconnect between what clinicians prioritize and what patients actually need

  • Consumerizing medical devices - why diabetes tech still feels like a Game Boy

  • WellDoc, Bigfoot Biomedical, and the lineage of connected insulin delivery

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